Bladder Cancer Panel +3,+7,+17,9p21-
Use
FISH panel test on urine specimens for the detection and monitoring of patients suspected of having bladder cancer. Includes probes to detect gains of chromosomes 3, 7, and 17, and loss of the p-arm of chromosome 9. The FDA-approved Vysis Urovysion Bladder Cancer assay can be performed upon request.
Special Instructions
Specimen should be voided urine mixed with preservative at a 2:1 ratio of urine to preservative (PreservCyt® or Carbowax® solutions) for a total volume > 50 mL. Shipping should be done refrigerated with precautions against extreme temperatures.
Limitations
Samples exposed to extreme temperature, incorrect preservative, insufficient volume or number of cells, or non-urine specimens including bladder or renal pelvic washings will be rejected. Specimen transport must not exceed 48 hours.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
> 33 mL
Minimum Volume
Not provided
Collection Instructions
Voided urine must be > 33 mL. Mix voided urine with preservative at 2:1 ratio of urine to preservative (PreservCyt® or Carbowax® solutions) for a total volume > 50 mL.
Storage Instructions
Urine: 2°C to 8°C. Protect from extreme temperature.
Causes for Rejection
Any non-urine specimen including bladder or renal pelvic washings; Incorrect preservative; Sample exposed to extreme temperature; Insufficient volume or number of cells for analysis; Specimen transport greater than 48 hours
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 72 hours |