Calcitonin
Use
Calcitonin is a peptide hormone produced by the C cells of the thyroid gland, involved in the regulation of calcium homeostasis by inhibiting bone resorption. It is used as a tumor marker for diagnosing and monitoring medullary thyroid carcinoma, a rare type of thyroid cancer that originates from the C cells.
Special Instructions
Fresh tissues should be fixed in formalin for a duration of 24-72 hours by collection sites, and then they can be transferred to 70% ethanol and stored at 2-8°C if longer term storage is needed. This is not preferred, and samples must be tested within 3 months after placing in ethanol. Slides used must be positively charged to prevent background staining and tissue loss, and should be left unbaked.
Limitations
Stated turnaround times are for clinical use only and may change based on biopharma protocol requirements. The final turnaround time will be specified in the biopharma study contract. Specimens not fixed in 10% NBF or B plus fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
8 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block, Formalin Fixed
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |