CAM5.2 (CK 7/8), technical only
Use
Low molecular weight keratin that primarily reacts with human keratin proteins corresponding to Moll's peptides #7 (KRT7, 48 KD) and #8 (KRT8, 52 KD) found in secretory epithelia of normal human tissue and associated adenocarcinomas. This is solely for technical purposes and does not include pathologist interpretation.
Special Instructions
The technical component does not include a pathologist read. Stated turnaround times (TATs) are for clinical use and are subject to change based on biopharma protocol requirements. Final TATs are specified in the biopharma study contract.
Limitations
Specimens should be tested within three months of being stored in ethanol. Specimens must be fixed in formalin for 24-72 hours before transfer to 70% ethanol for longer-term storage, which should be maintained at 2-8°C. This storage method, however, is not preferred.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Container
Formalin Fixed
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF), for 6-72 hours, with 48-72 hours being preferred.
Storage Instructions
Maintain at 15°C to 25°C. Use ambient conditions for shipping.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |