Carcinoembryonic antigen (CEA)
Use
Carcinoembryonic antigen (CEA) is an epithelial marker used to assist in the distinction between adenocarcinoma and mesotheliomas. CEA is also useful for identifying the origin of various metastatic adenocarcinomas when used in a panel of antibodies.
Special Instructions
Fresh tissues should be fixed in formalin for 24-72 hours and can be transferred to 70% ethanol and stored at 2-8°C if longer storage is required. Slides should be positively charged to prevent background staining and tissue loss.
Limitations
Specimens fixed in any fixative other than 10% neutral buffered formalin (NBF) or B plus will be rejected. Samples must be tested within 3 months if transferred to ethanol.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Specimens can be stored at 15°C to 25°C.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |