CD103
Use
CD103 is a heterodimeric transmembrane surface receptor that is expressed by several cell types of the immune system and is involved in cell to cell or cell to matrix interactions. CD103 is also a diagnostic tool in the detection of hairy cell leukemia (HCL) and hairy cell leukemia variant (HCL-v).
Special Instructions
Fresh Tissues may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides require positively charged glass slides to prevent background staining and tissue loss.
Limitations
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected. Stained slides and FFPE blocks are stable indefinitely, but fresh tissue must be stabilized within 72 hours.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours, with 48-72 hours preferred.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |