CD20
Use
CD20 is a transmembrane phosphoprotein expressed on B lineage cells. Expression continues throughout all stages of B-cell maturation until reaching the pro-B cell and plasma cell stage. CD20 antigen is observed on some precursor B lymphoid neoplasms, mature B-cell neoplasms, nodular lymphocyte predominant Hodgkin lymphoma, and in a subset of classical Hodgkin lymphomas.
Special Instructions
Specimens can be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for long-term storage if needed. For unstained slides, positively charged glass slides are required to prevent background staining and tissue loss.
Limitations
Stated turn-around-times are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block, Formalin Fixed
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin for 6-72 hours, preferred 48-72 hours.
Storage Instructions
Store at 15°C to 25°C. Ambient shipping with a refrigerated gel pack to protect from extreme temperatures.
Causes for Rejection
Specimens fixed in any fixatives other than 10% NBF or B plus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |
| Refrigerated | Indefinite |