CD38, technical only
Use
CD38 is one of the earliest markers of mature naïve B-cell activation and is strongly expressed on plasma cells. Low to moderate levels of expression can be observed in various hematopoietic cells (T-cells, natural killer cells) and in some solid tissues. CD38 IHC is useful in classifying functional mature B-lymphocyte subsets.
Special Instructions
Technical component only. Pathologist read not included.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
Storage Instructions
Fresh Tissues and Formalin-fixed Paraffin Embedded Tissue (FFPE blocks) should be stored at 15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | <= 72 Hours |