CD42b
Use
CD42b glycoprotein is expressed on the cell surface of megakaryocytes in bone marrow and platelets in blood vessels. Occasional staining is also observed in the basal epithelial of skin. Absence of CD42b antigen on platelets is reported to be a possible indicator of Bernard-Soulier disease.
Special Instructions
Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.
Limitations
Stained slides have indefinite stability. All specimens must be fixed in 10% neutral buffered formalin (NBF) or B plus. All other fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Storage Instructions
Store at 15°C to 25°C. Transfer to 70% alcohol for transportation after formalin fixation.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |
| Frozen | Indefinite |