CD56
Use
CD56 is a neural cell adhesion molecule found on the cell surface of neurons, astrocytes, Schwann cells, natural killer (NK) cells, and a subset of activated T lymphocytes. CD56 is useful in the determination of neuroendocrine tumors as well as some subsets of T-cell and NK-cell lymphomas.
Special Instructions
Fresh tissues should have a 20:1 fixative to tissue ratio with 10% neutral buffered formalin for 6-72 hours (preferably 48-72 hours). Formalin-fixed paraffin-embedded tissues must adhere to specimen stability guidance. Use positively charged slides to prevent background staining and tissue loss. Samples must be tested within 3 months if transferred to 70% ethanol.
Limitations
Specimens fixed in non-standard fixatives will be rejected. Turnaround times are subject to change based on biopharma protocol requirements. Samples must be tested within 3 months of being placed in ethanol.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin for 6-72 hours (48-72 hours preferred).
Storage Instructions
Store at 15°C to 25°C. For longer term storage, specimens may be placed in 70% ethanol and stored at 2-8°C.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |