CD56, technical only
Use
CD56 is a neural cell adhesion molecule found on the cell surface of neurons, astrocytes, Schwann cells, natural killer (NK) cells, and a subset of activated T lymphocytes. CD56 is useful in the determination of neuroendocrine tumors as well as some subsets of T-cell and NK-cell lymphomas. Technical component only. Pathologist read not included.
Special Instructions
Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer-term storage if needed. Samples must be tested within 3 months after placing in ethanol. Unstained slides require positively charged glass slides to prevent background staining and tissue loss. Slides should be left unbaked.
Limitations
This test does not include a pathologist read. The test is only for the technical component and requires appropriate specimen fixation. Other fixatives besides 10% neutral buffered formalin or B plus are not accepted. Fresh tissues should not exceed 72 hours in stability.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 hours |