CD7, technical only
Use
CD7 antigen is found on the surface of mature T-cells and natural killer (NK) cells. This marker is useful as part of an antibody panel designed to classify tumors of T-cell origin such as T-ALL, anaplastic large cell lymphomas, angioimmunoblastic T-cell lymphoma, T/NK cell lymphomas, lymphoblastic lymphomas, and thymoma. Technical component only. Pathologist read not included.
Special Instructions
Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.
Limitations
This test does not include a pathologist's read. It is the technical component only, and as such does not provide interpretive results. Results should be correlated with additional clinical data and the pathologist's analysis for complete diagnostic information. The stability of fresh tissues is limited to 72 hours when not transferred to ethanol for longer storage.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Store at 15°C to 25°C. Specimens may be transferred to 70% alcohol for transportation purposes after fixation in 10% NBF or B plus.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |