CD71
Use
CD71 is a transferrin receptor that mediates iron uptake in erythroid precursor cells within the normal hematopoietic marrow and spleen. This marker may be used in gestational pathology to identify nucleated red blood cells in conjunction with glycophorin A, which is expressed throughout all erythroid cell maturation stages. In hematopathology, CD71 is a useful marker for the diagnosis of acute erythroleukemia.
Special Instructions
Fresh Tissues can be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested within 3 months after placing in ethanol. Unstained slides require positively charged glass slides to prevent background staining and tissue loss, and should be left unbaked.
Limitations
Stated turnaround-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
15°C to 25°C. Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |