CD79a, technical only
Use
CD79a is a pan B-cell marker that first appears during the pre-B-cell stage, early in maturation, and persists until the plasma cell stage where it's found intracellularly. It is useful as a marker in antibody panels to differentiate classic Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma and aggressive B-cell lymphomas that may show Hodgkin-like features.
Special Instructions
Technical component only. Pathologist read not included. Fresh tissues should be fixed in formalin for 24-72 hours, then transferred to 70% ethanol and stored at 2-8°C for longer storage. Unstained slides should be positively charged to prevent background staining and tissue loss.
Limitations
The test does not include a pathologist interpretation and is limited to the technical component only. Stated turn-around-times are for clinical use only and subject to change based on biopharma protocol requirements.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Container
Formalin-fixed paraffin embedded block, unstained slides
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Store at 15°C to 25°C. For longer storage after fixation, transfer to 70% alcohol and store at 2-8°C.
Causes for Rejection
Specimens not fixed in 10% NBF or B plus will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 Hours |