CK 8/18, technical only
Use
Cytokeratins (CK) 8 and 18 are major components of the intermediate filaments in thyroid, liver and most simple epithelia. CK8/18 can be used as a marker to aid in the identification of adenocarcinomas and squamous cell carcinomas, Paget cells, metastatic gastric and colorectal carcinomas. Technical component only.
Special Instructions
Not provided.
Limitations
No pathologist read is included in the test offer. Specimens must be tested within 3 months after being placed in ethanol. Positively charged glass slides are required to prevent background staining and tissue loss. Slides should be left unbaked.
Methodology
Immunoassay (IHC)
Biomarkers
Cytokeratin 18
ProteinCytokeratin 8
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Store at 15°C to 25°C
Causes for Rejection
Specimens not fixed in 10% NBF or B plus will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |