DNAM1
Use
DNAM-1 is a platelet and T-cell activation antigen found on natural killer (NK) cells, platelets, monocytes, and subsets of B- and T- cells. This test is intended for use in clinical trial or research settings to study the role of DNAM-1 in various immune cell functions and its potential as a therapeutic target.
Special Instructions
Fresh tissues should be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol for longer-term storage if needed. Unstained slides require positively charged glass to prevent background staining and tissue loss. Samples must be tested within 3 months after transferring to ethanol.
Limitations
This test is for research use only and is not intended for diagnostic procedures. Results from this test can be influenced by the fixation and storage conditions of the specimen. Specimens not properly fixed or with inappropriate storage conditions may lead to unreliable results. The test is subject to changes based on the protocol requirements of specific biopharma studies.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fresh tissues should be fixed in 10% neutral buffered formalin at a 20:1 fixative to tissue ratio for 6-72 hours (48-72 hours preferred).
Storage Instructions
Store between 15°C to 25°C.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |