Factor X111a
Use
Factor XIIIa is a blood proenzyme expressed in platelets, cells of monocyte/macrophage myeloid lineage, and fibroblast-like mesenchymal and histiocytic cells. The Factor XIIIa antibody is useful in identifying fibrohistiocytic proliferations and dermal dendrocytes, primarily surrounding microvasculature in the adventitial dermis near the dermoepidermal junction and near skin appendages.
Special Instructions
Specimens must be fixed in 10% neutral buffered formalin (NBF) or B plus. Fresh specimens can be transferred to 70% ethanol after formalin fixation for longer-term storage. Unstained slides require positively charged glass slides to prevent background staining and tissue loss.
Limitations
Stated turnaround times are for clinical use only and may vary based on biopharma protocol requirements. The testing must be performed within three months of placing samples in ethanol.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block
Collection Instructions
Fix with a 20:1 ratio of fixative to tissue in 10% neutral buffered formalin for 6-72 hours (48-72 hours preferred).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens not fixed in 10% NBF or B plus will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |