Factor X111a, technical only
Use
Factor XIIIa is a blood proenzyme expressed in platelets and cells of monocyte/macrophage myeloid lineage, as well as in fibroblast-like mesenchymal and histiocytic cells. It is useful in identifying fibrohistiocytic proliferations and dermal dendrocytes, especially near microvasculature in the adventitial dermis near the dermoepidermal junction and near skin appendages.
Special Instructions
Technical component only, pathologist read not included. Fresh tissues need formalin fixation at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin for 6-72 hours (48-72 hours preferred). Positive charged glass slides are required to prevent background staining and tissue loss.
Limitations
Stated turn-around-times are for clinical use only and subject to change based on biopharma protocol requirements.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours preferred).
Storage Instructions
Specimens may be transferred to 70% alcohol for transportation purposes after fixation in 10% NBF or B plus.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |