Fascin, technical only
Use
Fascin is an actin-binding protein that plays a key role in cell migration, invasion, and the formation of actin filaments in epithelial cells. In pathology, fascin is used to distinguish metastatic tumors from benign lesions, as it is frequently overexpressed in tumors such as breast, ovarian, and colorectal cancers. Technical component only. Pathologist read not included.
Special Instructions
Not provided.
Limitations
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected. The test does not include a pathologist read and is technical only.
Methodology
Immunoassay (IHC)
Biomarkers
Fascin
Protein
Result Turnaround Time
7 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Ambient. Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |