FOXP3
Use
Forkhead box P3 (FOXP3) is a transcription factor expressed in regulatory T-cells. FOXP3 functions as a master regulator of the development and function of natural T regulatory cells (nTregs) and adaptive / induced T regulatory cells (a / iTregs).
Special Instructions
Fresh tissues should be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Unstained slides require positively charged glass slides to prevent background staining and tissue loss. Slides should be left unbaked.
Limitations
Specimens fixed in other than 10% neutral buffered formalin will be rejected. Turnaround times are subject to change based on biopharma protocol requirements and may be further specified in biopharma study contracts.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 Hours |
| Refrigerated | Indefinite |