FOXP3, technical only
Use
Forkhead box P3 (FOXP3) is a transcription factor expressed in regulatory T-cells. FOXP3 functions as a master regulator of the development and function of natural T regulatory cells (nTregs) and adaptive / induced T regulatory cells (a / iTregs).
Special Instructions
Technical component only. Pathologist read not included. Specimens may be transferred to 70% alcohol for transportation purposes after fixation in 10% NBF or B plus.
Limitations
Stated turnaround times are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Specimens may be transferred to 70% alcohol for transportation purposes after fixation in 10% NBF or B plus.
Causes for Rejection
All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |