Hairy cell leukemia (DBA44), technical only
Use
The DBA44 protein marker is a surface antigen associated with hairy cell leukemia (HCL), which is primarily expressed on the abnormal B-cells characteristic of this disorder. In pathology, DBA44 is used to help differentiate HCL from other B-cell lymphomas, as it is highly specific for HCL cells. Technical component only. Pathologist read not included.
Special Instructions
Not provided.
Limitations
This test provides technical information only and does not include a pathologist's interpretation. The specificity of DBA44 to hairy cell leukemia is highly regarded, but its presence alone should not be used for a conclusive diagnosis without correlation with clinical findings and other laboratory tests.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |