HMB 45, technical only
Use
The human melanoma black (HMB) antibody reacts with neuraminidase-sensitive oligosaccharide side chains of glycoconjugates present in immature melanosomes, cutaneous melanocytes, prenatal/infantile retinal pigment epithelium (RPE), and melanoma cells. Studies support the routine use of HMB45 as a sensitive and specific melanocytic marker.
Special Instructions
Not provided.
Limitations
Specimens must be adequately fixed in 10% neutral buffered formalin. Use of other fixatives will result in specimen rejection. The test provides only a technical result and requires pathologist interpretation for clinical diagnosis.
Methodology
Immunoassay (IHC)
Biomarkers
HMB45
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |