I CD155

Casandra

Casandra Test Code MP88009Version 1 (DRAFT)

Performing Lab

Lab MPLNLab Test ID I CD155

Clinical Use

Use

CD155 is a cell surface protein involved in cell adhesion and immune modulation, particularly through interactions with immune checkpoint receptors. In pathology, CD155 serves as an important marker for assessing tumor progression, particularly in malignancies like head and neck squamous cell carcinoma and melanoma, where its expression correlates with increased tumor invasiveness and poor prognosis.

Special Instructions

This test is available for use in clinical trials or research purposes only. Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer-term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.

Limitations

Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract. Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.

Test Details

Methodology

Immunoassay (IHC)

Biomarkers

CD155

Protein

IHC • Expression • Categorical (e.g., Positive / Negative / Indeterminate)

Result Turnaround Time

2 days

Specimen

Tissue (Fresh)

Volume

Not provided

Minimum Volume

Not provided

Collection Instructions

Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED). Samples may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer-term storage if needed. Samples must be tested 3 months after placing in ethanol.