IGH::MYC; t(8;14)
Use
The FISH test on hematologic specimens is used for detecting the IGH::MYC gene fusion associated with t(8;14). This gene fusion is associated with Burkitt lymphoma and may support its diagnosis when considered alongside clinical, immunophenotypic, and morphologic context. However, the fusion may also occur in the progression of other lymphomas and plasma cell neoplasms. It is often ordered as part of the F BURKITT Panel test.
Special Instructions
All attempts will be made to process and report samples received more than 72 hours post-collection. Bone marrow is the sample of choice in most hematologic malignancies.
Limitations
The stated turnaround times are for clinical use only and may change based on specific biopharma protocol requirements. Final terms will be specified in the corresponding biopharma study contract. Specimens are prone to rejection if clotted, exposed to extreme temperature, treated with anticoagulants toxic to cells, or if they contain an insufficient number of cells.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
Not provided
Container
EDTA preferred (NaHep accepted)
Storage Instructions
2°C to 25°C
Causes for Rejection
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |