Neuron Specific Enolase
Use
Neuron specific enolase is a cytoplasmic enzyme expressed by neuroendocrine cells and tumors, including poorly differentiated neuroendocrine tumors.
Special Instructions
Special considerations for fresh tissues include fixing specimens in formalin for 24-72 hours, then transferring to 70% ethanol for longer storage. Unstained slides should be on positively charged glass to prevent background staining and tissue loss.
Limitations
Stated turn-around-times are subject to change based on biopharma protocol. Only specimens fixed in 10% NBF or B plus will be accepted as others will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be used at a 20:1 fixative to tissue ratio, and specimens should be fixed in 10% neutral buffered formalin for 6-72 hours (48-72 hours preferred).
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |