OCT-2
Use
OCT-2 is a B-cell restricted transcription factor of the POU homeo-domain family that binds the Ig gene to regulate B-cell-specific genes. OCT-2 is found in several B-cell neoplasms including myeloma, differentiate nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), and classical Hodgkin lymphoma (CHL).
Special Instructions
Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested within 3 months after placing in ethanol.
Limitations
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected. Unstained slides require positively charged glass slides to prevent background staining and tissue loss. Fresh tissues should be transferred to 70% alcohol after fixation for transportation. Slides should be left unbaked.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Store at 15°C to 25°C.
Causes for Rejection
Specimens not fixed in 10% NBF or B plus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |