Pan-TRK, technical only
Use
Pan-TRK detection of the C-terminal region of the tropomyosin receptor kinase (TRK) proteins A, B, and C via immunohistochemistry. This test includes only the technical component, meaning that it does not include a pathologist's interpretation. It is used for the detection of TRK proteins, which are involved in the development of various cancers due to gene fusions.
Special Instructions
Not provided.
Limitations
This test does not include a pathologist's interpretation, and the results are only technically provided without clinical correlation. Specimens must be fixed in 10% neutral buffered formalin (NBF) or B plus. Other fixatives will be rejected. Turnaround times are subject to change based on biopharma protocol requirements.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours, with 48-72 hours preferred. Specimens may be transferred to 70% alcohol for transportation purposes after fixation.
Storage Instructions
Store specimens at 15°C to 25°C. If transferred to ethanol, store at 2-8°C for long-term.
Causes for Rejection
All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |