PAX-5, technical only
Use
PAX-5 is a B-cell specific nuclear transcription factor that is expressed in pre-B, pro-B, and mature B-cell stages. Detection of PAX-5 is recommended as part of an antibody panel for the identification of B-cell malignancies. Technical component only, not including pathologist interpretation.
Special Instructions
Not provided.
Limitations
The test is technical only without a pathologist's read, limiting its utility in providing a comprehensive diagnostic interpretation of B-cell malignancies. The fixation and storage conditions must be strictly followed to prevent degradation of tissue samples.
Methodology
Immunoassay (IHC)
Biomarkers
PAX-5
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours preferred).
Storage Instructions
Store at 15°C to 25°C.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |