ProExC™ Biomarker
Use
ProExC™ is a biomarker panel consisting of overexpressed proteins such as cyclin E and minichromosome maintenance proteins (MCM2, MCM3, and MCM5), which are associated with cell cycle dysregulation and increased cellular proliferation. In pathology, ProExC™ is used to identify high-risk lesions, particularly in cervical and other squamous cell carcinomas, by assessing the degree of cellular proliferation.
Special Instructions
Not provided.
Limitations
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
8 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |