ProExC™ Biomarker, technical only
Use
ProExC™ is a biomarker panel consisting of overexpressed proteins such as cyclin E and minichromosome maintenance proteins (MCM2, MCM3, and MCM5), which are associated with cell cycle dysregulation and increased cellular proliferation. In pathology, ProExC™ is used to identify high-risk lesions, particularly in cervical and other squamous cell carcinomas, by assessing the degree of cellular proliferation. Technical component only. Pathologist read not included.
Special Instructions
Not provided.
Limitations
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected. The test is technical only, meaning pathologist read is not included in the service.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |