Casandra
Casandra Test Code MP45976Version 1 (DRAFT)
Performing Lab
Lab MPLNLab Test ID I PTEN
PTEN
Clinical Use
Order TestUse
PTEN (phosphatase and tensin homolog deleted on chromosome 10) is a tumor suppressor whose loss permits constitutive signaling through the PI3K pathway. In normal cells, PTEN restricts cell growth and cell migration.
Special Instructions
Not provided.
Limitations
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Test Details
Methodology
Immunoassay (IHC)
Biomarkers
PTEN Immunohistochemistry • IHC
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block, Formalin Fixed
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |