Renal cell carcinoma, technical only
Use
Renal cell carcinoma (RCC) protein marker is a cell membrane antigen that is highly expressed in clear cell RCC. This marker is especially helpful in distinguishing RCC from other malignancies with similar histological features, such as oncocytomas and urothelial carcinomas. Technical component only. Pathologist read not included.
Special Instructions
Fresh tissues should be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol for longer storage at 2-8°C if needed. Samples must be tested within 3 months after transferring to ethanol. Unstained slides should use positively charged glass to avoid background staining and tissue loss.
Limitations
This test covers only the technical component; a pathologist's interpretation is not included. Specimens fixed using non-standard fixatives apart from 10% NBF or B plus will be rejected. Stability of fresh tissues is limited to 72 hours only, requiring timely processing.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Unknown)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, using 10% neutral buffered formalin for 6-72 hours (48-72 hours preferred).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |