Casandra
Casandra Test Code MP75369Version 1 (DRAFT)
Performing Lab
Smooth Muscle Actin
Clinical Use
Order TestUse
Smooth muscle actin (SMA) is a key component of the cytoskeleton in smooth muscle cells and is commonly used in pathology for identifying smooth muscle tumors. SMA is expressed in smooth muscle tumors such as leiomyomas and leiomyosarcomas, as well as in myofibroblastic lesions.
Special Instructions
Not provided.
Limitations
Tests must be performed within three months after ethanol storage. Specimens must be fixed in 10% NBF or B plus; all other fixatives will be rejected.
Test Details
Methodology
Immunoassay (IHC)
Biomarkers
Smooth Muscle Actin
ProteinIHC
Expression • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block, Unstained slides
Storage Instructions
Ambient, Use a refrigerated (NOT FROZEN) gel pack to protect from extreme temperatures.
Causes for Rejection
All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours (Fresh Tissue), Indefinite (FFPE blocks and Unstained slides) |