Smooth muscle myosin, technical only
Use
Smooth muscle myosin (SMM) is essential for the contraction of smooth muscle cells and is used in pathology to identify smooth muscle tumors. It is typically expressed in tumors such as leiomyomas and leiomyosarcomas, helping differentiate these tumors from other soft tissue malignancies, including fibromas and malignant fibrous histiocytomas. Technical component only. Pathologist read not included.
Special Instructions
Not provided.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
Smooth Muscle Myosin
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED). Specimens may be transferred to 70% alcohol for transportation purposes after fixation.
Storage Instructions
Store at 15°C to 25°C. For longer term storage, use 70% ethanol at 2-8°C.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |
| Frozen | Indefinite |