Somatostatin
Use
Somatostatin is a peptide hormone that inhibits the release of various other hormones and is expressed in certain neuroendocrine tumors, particularly those arising in the pancreas, gastrointestinal tract, and pituitary. In pathology, somatostatin is used to identify neuroendocrine tumors, such as somatostatinomas, which often produce high levels of the hormone. Its detection can also aid in distinguishing neuroendocrine tumors from other types of malignancies.
Special Instructions
Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.
Limitations
Specimens must be fixed in 10% neutral buffered formalin or B plus. All other fixatives will be rejected. Stated turnaround times are for clinical use only and subject to change based on protocol requirements.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
8 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin for 6-72 hours (48-72 hours PREFERRED).
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |