Synatophysin, technical only
Use
Synaptophysin is a membrane glycoprotein expressed in the synaptic vesicles of neurons and neuroendocrine cells. It is primarily used in pathology to identify neuroendocrine tumors, including neuroblastomas, small cell carcinomas, and pheochromocytomas, as these tumors typically show strong synaptophysin expression. This marker also helps differentiate neuroendocrine tumors from other types of malignancies with similar features. Technical component only. Pathologist read not included.
Special Instructions
Not provided.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Synaptophysin
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
Storage Instructions
Store at 15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |