SYT 18q11.2 Synovial Sarcoma
Use
FISH test for Synovial sarcomas, which account for 5-10% of soft tissue sarcomas, are seen mainly in adolescents and adults aged between 15 and 45 years. More than 85-95% of them arise in the deep soft tissues of the extremities. Synovial sarcomas harbor the t(X;18) translocation.
Special Instructions
Not provided.
Limitations
Test is subject to biopharma protocol requirements, and final TATs will be specified in the biopharma study contract. Samples must be shipped ambient or refrigerated with a gel pack to avoid extreme temperatures. Clotted specimens or those exposed to extreme temperatures are rejected.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Chromosome t(X;18)
Chromosome
Result Turnaround Time
9 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
Not provided
Container
EDTA preferred (NaHep accepted)
Storage Instructions
2°C to 25°C
Causes for Rejection
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |