TdT
Use
TdT is a DNA polymerase enzyme that is typically expressed in precursor lymphoid cells, such as those in acute lymphoblastic leukemia and certain other hematologic malignancies. In pathology, TdT is used to distinguish between different types of leukemia and lymphoma, particularly to identify T-cell and B-cell precursor leukemias.
Special Instructions
For fresh tissues, specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer-term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides require positively charged glass to prevent background staining and tissue loss.
Limitations
Stated turn-around-times are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block, Formalin Fixed
Storage Instructions
Ambient, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen.
Causes for Rejection
Specimens fixed in other than 10% NBF or B plus will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |