Trisomy 21
Use
An extra copy of chromosome 21 is the cause of Down syndrome. An increased risk is seen with the increase in maternal age. Testing is performed by an affiliate laboratory. This test is often used in prenatal diagnostics and is related to women's health concerns.
Special Instructions
All attempts will be made to process and report samples that are received more than 72 hours post-collection. Shipping should include a refrigerated (not frozen) gel pack to protect from extreme temperatures. Specimens should not be frozen.
Limitations
Specimen rejection criteria include clotted specimens, exposure to extreme temperatures, anticoagulants that are toxic to cells, and insufficient number of cells. Specimen stability is 72 hours, and specimens should be shipped ambient or refrigerated, not frozen.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
9 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
Not provided
Container
EDTA preferred (NaHep accepted)
Storage Instructions
Whole Blood should be stored at 2°C to 25°C.
Causes for Rejection
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells