TROP2
Use
TROP2 is a transmembrane glycoprotein involved in regulating cell proliferation and differentiation. It is often overexpressed in various epithelial cancers. In pathology, Trop2 is used to identify and assess the aggressiveness of carcinomas, particularly in cancers of the breast, colon, and lung, where its expression correlates with poor prognosis and metastatic potential.
Special Instructions
Not provided.
Limitations
This test is available for use in clinical trials or research purposes only. Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Specimens must be fixed in 10% NBF or B plus; all other fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
TROP2
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fresh Tissues: Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |