Vimentin
Use
Vimentin is an intermediate filament protein that provides structural support to cells and is primarily expressed in mesenchymal cells, including fibroblasts, endothelial cells, and smooth muscle cells. In pathology, vimentin is widely used to identify tumors of mesenchymal origin, such as sarcomas, and to differentiate these from epithelial and other types of malignancies.
Special Instructions
Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract. Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
4 mL
Minimum Volume
0.5 mL
Container
EDTA or NaHep
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |