Von Willebrand Factor VIII, technical only
Use
The von Willebrand factor (VWF) is a glycoprotein involved in platelet adhesion and aggregation, playing a critical role in hemostasis by stabilizing factor VIII in the blood clotting process. It is used in pathology to assess vascular endothelium and diagnose bleeding disorders like von Willebrand disease. Additionally, it helps in identifying endothelial tumors, such as hemangiomas and angiosarcomas.
Special Instructions
Technical component only. Pathologist read not included.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED). Ambient shipping conditions recommended, with protective measures against extreme temperatures.
Storage Instructions
15°C to 25°C. Fresh tissues may be fixed in formalin 24-72 hours, then transferred to 70% ethanol and stored at 2-8°C.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |