ACTH
Also known as: adrenocorticotropic hormone
Use
Anti-adrenocorticotropic hormone (ACTH) immunohistochemistry serves as a useful diagnostic marker for identifying ACTH-producing corticotroph cells, particularly useful in classifying pituitary tumors and evaluating pituitary disease. Additionally, this stain may react with non–pituitary tumors, for example small cell carcinoma of the lung, which can produce ectopic ACTH leading to paraneoplastic syndromes.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
ACTH
Protein
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2‑3) positively charged unstained slides (all cut at 4‑5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.