Annexin A1
Use
Annexin A1 (ANXA1) is a gene associated with phagocytosis and is highly upregulated in hairy cell leukemia. It is strongly expressed on the cell membrane in approximately 97% of classic hairy cell leukemia cases, enabling differentiation from other B-cell tumors where ANXA1 is negative, although expression may also occur in myeloid cells, macrophages, and subsets of benign T‑cells.
Special Instructions
Level of Service is Tech Only (technical component only).
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred, or one unbaked, unstained slide for H&E staining (required) plus two to three positively charged unstained slides cut at 4‑5 microns. Block and slide identifiers must match specimen labeling on the requisition.