BCL10
Use
BCL‑10 is an N‑terminal CARD (Caspase Recruitment Domain) containing protein involved in the adaptive immune response and a substrate for MALT1. Mutations in the gene can lead to lymphoma, mucosa-associated lymphoid tissue (MALT) lymphoma. The assay is useful in the assessment of pancreatic tumors to distinguish acinar cell carcinoma from primitive neuroectodermal tumor (PNET), solid pseudopapillary tumor (SPT), and pancreatic blastoma (PB).
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
BCL10
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin-fixed, paraffin‑embedded (FFPE) tissue block is preferred or one unbaked, unstained H&E slide (required) plus two to three positively charged unstained slides, 4–5 microns each. Block and slide identifiers must match requisition.
Storage Instructions
Use cold pack for transport; cold pack not in direct contact with specimen; NYS clients supply collection date and time.