BerEP4
Use
Ber‑EP4 is an immunohistochemical stain that recognizes two epithelial glycoproteins (~34 and 49 kDa) present on most epithelial cells—excluding superficial squamous epithelium, hepatocytes, and parietal cells—and rarely marks mesotheliomas. It is clinically useful to distinguish adenocarcinomas from mesotheliomas, especially in pleural specimens.
Special Instructions
Technical‑only service. Formalin‑fixed, paraffin‑embedded (FFPE) tissue block is the preferred specimen, or alternatively one unbaked unstained H&E slide (required) plus two to three positively charged unstained slides cut at 4–5 microns. Use cold pack for transport, avoiding direct contact with specimen. NYS clients must provide date and time of collection.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
FFPE tissue block preferred or one unbaked unstained H&E slide (required) plus 2‑3 positively charged unstained slides cut at 4‑5 microns.