Breast Triple Stain (CK5 + p63 + CK 8/18)
Use
The combination of CK5 + P63 + CK8/18 can be useful in distinguishing ductal carcinoma in situ (DCIS) from microinvasive breast carcinoma. This multiplex can decipher between a radial scar and infiltrating carcinoma. P63 (nuclear brown) and CK5/6 (cytoplasmic brown) stain myoepithelial cells, whereas CK8/18 labels the cytoplasm (red) of all ductal or lobular epithelium.
Special Instructions
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Limitations
Please direct any questions regarding coding to the payor being billed. Use cold pack for transport, making sure the cold pack is not in direct contact with specimen.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.