BRG1 (SMARCA4)
Use
BRG1 (SMARCA4) is involved in chromatin remodeling, which regulates the binding of transcription factors to DNA. Immunohistochemical loss of expression of BRG‑1 (SMARCA4) is associated with the diagnosis of small cell carcinoma of ovary, hypercalcemic type (SCCOHT). Clone: Polyclonal. Staining pattern: Nuclear.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
SMARCA4
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen type or one unbaked, unstained slide for H&E staining (required) and two to three positively charged unstained slides (4‑5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match specimen ID on requisition.
Storage Instructions
Use cold pack for transport, ensuring cold pack is not in direct contact with specimen.