Calponin
Use
Calponin is a smooth muscle–associated calmodulin protein, with expression largely restricted to smooth muscle cells and myoepithelial cells. It can help distinguish in situ from infiltrating breast carcinoma, owing to its expression pattern, including its 29 kDa urogenital smooth muscle–restricted isoform.
Special Instructions
Immunohistochemistry (IHC) test; requires formalin‑fixed, paraffin‑embedded (FFPE) tissue block preferred, or one unbaked, unstained H&E slide plus two to three positively charged unstained slides cut at 4‑5 microns. Blocks and slides must have clear labels matching specimen IDs. Use cold packs for transport; cold pack must not be in direct contact with specimen. For New York State clients, date and time of collection must be provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded tissue block preferred or one unbaked, unstained slide for H&E plus two to three positively charged unstained slides (4‑5 microns); block and slide identifiers must match specimen ID.
Storage Instructions
Use cold pack for transport; cold pack should not be in direct contact with specimen.