Calretinin
Use
Calretinin is the most specific and reproducible positive marker of epithelial mesothelioma. It is a calcium‑binding protein similar to S100, found in central and peripheral nervous systems and a wide array of non‑neural cells; calretinin immunostaining is observed in most epithelial mesotheliomas. This test helps to identify and support diagnosis of epithelial mesothelioma using immunohistochemical staining.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Calretinin
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen type or one unbaked, unstained slide for H&E staining (required) and two to three positively charged unstained slides (all cut at 4‑5 microns) for each test/antibody ordered. Block and slide identifiers should match exactly with the requisition.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.